Neuronal excitability and its role in disorders of the nervous system

Research topics:

        Mechanisms of neuronal excitability and plasticity

        Hippocampus; dentate gyrus; entorhinal cortex; “limbic” circuits

        Dysfunction in ‘complex’ disorders

                Epilepsy

                Aging and Alzheimer’s disease

        Neuroendocrinology; sex differences

Current research “streams”:

        Neurotrophins              

                    Estrogen and androgen actions

                    mediated by brain-derived

                    neurotrophic factor (BDNF)

       Neurogenesis in the adult dentate

                     gyrus

       Mossy cells of the dentate gyrus