Bibliography

ORIGINAL REPORTS

  1. Scharfman HE and Sarvey JM (1985) Postsynaptic firing during repetitive stimulation is required for long-term potentiation in hippocampus. Brain Res. 331:267-274.
  2. Scharfman HE and Sarvey JM (1985) GABA sensitivity does not change during long-term potentiation in rat hippocampal slices. Neuroscience. 15:695-702.
  3. Scharfman HE and Sarvey JM (1985) Responses to g-aminobutyric acid applied to cell bodies and dendrites of rat visual cortical neurons. Brain Res. 358:385-389.
  4. Scharfman HE and Sarvey JM (1987) Responses to g-aminobutyric acid (GABA) recorded from identified rat visual cortical neurons. Neuroscience. 23:407-422.
  5. Scharfman HE and Sarvey JM (1988) Physiological correlates of responses to g-aminobutyric acid (GABA) recorded from rat visual cortical neurons in vitro. Synapse. 2:619-626.
  6. Scharfman HE and Schwartzkroin PA (1988) Electrophysiology of morphologically identified mossy cells of the rat dentate hilus. J. Neurosci. 8:3412-3421.
  7. Scharfman HE and Schwartzkroin PA (1988) Further studies of somatostatin and related peptides in area CA1 of rabbit hippocampus studied in vitro. Cell. and Mol. Neurobiol. 8:4ll-429.
  8. Scharfman HE, Kunkel DD and Schwartzkroin PA (1989) Intracellular dyes mask immunoreactivity of hippocampal neurons. Neurosci. Lett. 96:23-28.
  9. Scharfman HE and Schwartzkroin PA (1989) Selective depression of GABA-mediated IPSPs by somatostatin in area CA1 of rabbit hippocampus. Brain Res. 493:205-211.
  10. Scharfman HE and Schwartzkroin PA (1989) Protection of dentate hilar mossy cells from prolonged stimulation by intracellular calcium chelation. Science. 246:257-260.
  11. Scharfman HE and Schwartzkroin PA (1990) Responses of cells of the fascia dentata to prolonged stimulation of the perforant path: sensitivity of hilar cells and changes in granule cell excitability. Neuroscience. 35:491-504.
  12. Scharfman HE and Schwartzkroin PA (1990) Consequences of prolonged afferent stimulation of the rat fascia dentata: epileptiform activity in area CA3 of hippocampus. Neuroscience. 35:505-517.
  13. Scharfman HE and Schwartzkroin PA (1990) Synaptic connections of dentate granule cells and hilar neurons established by simultaneous intracellular recording in rat hippocampal slices. Neuroscience. 37:693-707.
  14. Scharfman HE, Lu FS, Guido W, Adams PR and Sherman SM (1990) N-methyl-D-aspartate (NMDA) receptors contribute to EPSPs of cat lateral geniculate neurons recorded in thalamic slices. Proc. Natl. Acad. Sci. U.S.A. 86:1056-1060.
  15. Scharfman HE (1991) Dentate hilar cells with dendrites in the molecular layer have lower thresholds for synaptic activation by perforant path than granule cells. J. Neurosci. 11:1660-1673.
  16. Scharfman HE (1992) Blockade of excitation reveals inhibition in dentate spiny hilar cells of rat hippocampal slices. J. Neurophysiol. 68:978-984.
  17. Kunkel DD, Scharfman HE and Schwartzkroin PA (1993) Electron microscopy of intracellularly labeled neurons in the hippocampal slice preparation. J. Elec. Microscope. Tech. 24:67-84.
  18. Scharfman HE (1993) Spiny neurons of area CA3c in rat hippocampal slices have similar electrophysiological properties and synaptic responses despite morphological variation. Hippocampus. 3:9-28.
  19. Scharfman HE (1993) Activation of dentate hilar neurons by stimulation of the fimbria in rat hippocampal slices. Neurosci. Lett. 156:61-66.
  20. Scharfman HE (1993) Characteristics of spontaneous and evoked EPSPs recorded from dentate spiny hilar cells in rat hippocampal slices. J. Neurophysiol. 70:742-757.
  21. Scharfman HE (1994) Synchronization of area CA3 hippocampal pyramidal cells and non-granule cells of the dentate gyrus in bicuculline-treated rat hippocampal slices. Neuroscience. 59:245-257.
  22. Scharfman HE (1994) Paradoxical enhancement of GABAA receptor-mediated IPSPs of dentate granule cells by bicuculline in rat hippocampal slices. Neurosci. Lett. 168:29-33.
  23. Scharfman HE (1994) EPSPs of dentate gyrus granule cells synchronized with epileptiform bursts of dentate hilar mossy cells and area CA3 pyramidal cells in disinhibited rat hippocampal slices. J. Neurosci. 14:6041-6057.
  24. Scharfman HE (1994) Evidence from simultaneous intracellular recordings in rat hippocampal slices that area CA3 pyramidal cells innervate dentate hilar mossy cells. J. Neurophysiol. 72:2167-2180.
  25. Scharfman HE (1995) Electrophysiological evidence that dentate hilar mossy cells innervate both granule cells and interneurons. J. Neurophysiol. 74:179-194.
  26. Scharfman HE (1995) Electrophysiological diversity of pyramidal-shaped neurons at the granule cell layer/hilus border of the rat dentate gyrus recorded in vitro. Hippocampus. 5:287-305.
  27. Scharfman HE (1996) Conditions required for polysynaptic excitation of dentate granule cells by area CA3 pyramidal cells in rat hippocampal slices. Neuroscience. 72:655-668.
  28. Jackson MB and Scharfman HE (1996) Positive feedback from hilar mossy cells to granule cells in the dentate gyrus revealed by voltage-sensitive dye and microelectrode recording. J. Neurophysiol. 76:601-616.
  29. Scharfman HE (1997) Hyperexcitability of entorhinal cortex and hippocampus after application of amino-oxyacetic acid (AOAA) to medial entorhinal cortex in combined entorhinal and hippocampal slices. J. Neurophysiol. 76:2986-3001.
  30. Scharfman HE and Ofer AA (1997) Pretreatment with L-kynurenine, the precursor to the excitatory amino acid antagonist kynurenic acid, suppresses epileptiform activity in combined entorhinal/hippocampal slices. Neurosci. Lett. 224:115-118.
  31. Scharfman HE (1997) Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor. J. Neurophysiol. 78:1082-1095.
  32. Scharfman HE and Goodman JH (1998) Effects of central and peripheral administration of kynurenic acid on hippocampal evoked responses in vivo and in vitro. Neuroscience. 86:751-764.
  33. Scharfman HE, Goodman JH, Du F and Schwarcz R (1998) Chronic changes in synaptic responses of entorhinal and hippocampal neurons after amino-oxyacetic acid (AOAA)- induced entorhinal cortical neuron loss. J. Neurophysiol. 80:3031-3046.
  34. Scharfman HE, Goodman JH and Sollas AL (1999) Actions of BDNF in slices from rats with spontaneous seizures and mossy fiber sprouting in the dentate gyrus. J. Neurosci. 19:5619-5631.
  35. Croll SD, Suri C, Compton DL, Simmons MV, Yancopoulos GD, Lindsay RM, Wiegand SJ and Scharfman HE (1999) Brain-derived neurotrophic factor (BDNF) transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience. 93:1491-1506.
  36. Scharfman HE, Hodgkins PS, Lee SC and Schwarcz R (1999) Quantitative differences in the effects of de novo produced and exogenous kynurenic acid in rat brain slices. Neurosci. Lett. 274:111-114.
  37. Wu HQ, Guidetti P, Goodman JH, Varasi M, Cersoli-Borroni G, Speciale C, Scharfman HE and Schwarcz R (2000) Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo. Neuroscience. 97:243-251.
  38. Scharfman HE, Goodman JH and Sollas AL (2000) Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. J. Neurosci. 20:6144-6158.
  39. Scharfman HE, Smith KS, Goodman JH and Sollas AL (2001) Survival of dentate hilar mossy cells after pilocarpine-induced seizures and their synchronized burst discharges with area CA3 pyramidal cells. Neuroscience. 104:741-759.
  40. Scharfman HE, Sollas AL and Goodman JH (2001) Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus. Neuroscience. 111:71-81.
  41. Scharfman HE, Goodman JH, Sollas AL and Croll SD (2002) Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor (BDNF). Exp. Neurol. 174:201-214.

43.Wu HQ, Lee SC, Scharfman HE and Schwarcz R (2002) L-4-chlorokynurenine attenuates kainate-induced seizures and lesions in the rat. Exp. Neurol. 177:1-11.

  1. Scharfman HE, Goodman JH, Sollas AL, Smith KL and Jackson MB (2002) Structural and functional asymmetry in the normal and epileptic dentate gyrus. J. Comp. Neurol. 454:424-439.
  2. Howell OW, Scharfman HE, Beck-Sickinger AG, Herzog HH and Gray WP (2003) Neuropeptide Y is neuroproliferative for hippocampal stem cells and neuroblasts. J. Neurochem. 86:646-659.
  3. Scharfman HE, Sollas AL, Berger RE and Goodman JH (2003) Electrophysiological evidence of monosynaptic excitatory transmission between granule cells following seizure-induced mossy fiber sprouting. J. Neurophysiol. 90:2536-2547.
  4. Scharfman HE, Sollas AL, Berger RE, Goodman JH and Pierce JP (2003) Perforant path activation of ectopic granule cells that are born after pilocarpine-induced seizures. Neuroscience. 121:1017-1029.
  5. Scharfman HE, Mercurio TC, Goodman JH, Wilson MA and MacLusky NJ (2003) Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. J. Neurosci. 23:11641-11652.
  6. Scharfman HE, Goodman JH, MacLeod A, Phani S, Antonelli C, and Croll SD (2005) Increased neurogenesis and ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp. Neurol. 192:348-356.
  7. Howell OW, Doyle K, Goodman JH, Scharfman HE, Herzog H, Pringle A, Beck-Sickinger AG and Gray WP (2005) Neuropeptide Y stimulates neuronal precursor proliferation in the postnatal and adult dentate gyrus. J. Neurochem. 93:560-570.
  8. Wu HQ, Rassoulpour A, Goodman JH, Scharfman HE, Bertram EH, and Schwarcz R (2005) Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats. Epilepsia. 46:1010-1016.
  9. 53. Scharfman HE, Goodman JH, Rigoulot MA, Berger RE, Walling SG, Mercurio TC, Stormes KA and MacLusky NJ (2005) Seizure susceptibility in intact and ovariectomized female rats treated with the convulsant pilocarpine. Exp. Neurol. 196:73-86.
  10. McCloskey DP, Croll SD, Scharfman HE (2005) Depression of synaptic transmission by vascular endothelial growth factor in adult rat hippocampus and evidence for increased efficacy after chronic seizures. J. Neurosci. 25:8889-8897.
  11. Pierce JP, Melton J, Punsoni, M, McCloskey DP, and Scharfman HE (2005) Mossy fibers are the primary source of afferent input to ectopic granule cells that are born after pilocarpine-induced seizures. Exp. Neurol. 196:316-331.
  12. McCloskey DP, Hintz T, Pierce JP and Scharfman HE (2006) Stereological estimation of the number of ectopic granule cells in the hilus following pilocarpine-induced status epilepticus. Eur. J. Neurosci. 24:2203-2210.
  13. Scharfman HE, Goodman JH, and McCloskey DP (2007) Ectopic granule cells of the rat dentate gyrus. Dev. Neurosci. 29:14-27.
  14. Howell OW, Silva S, Scharfman HE, Sosunov AA, Zaben M, McKhann GM, Lawskowski A and Gray WP (2007) Neuropeptide Y is important for basal and seizure induced precursor cell proliferation in the hippocampus. Neurobiol. Dis. 26:174-188.
  15. Pierce JP, Punsoni M, McCloskey DP and Scharfman HE (2007) Mossy cell axon synaptic contacts on ectopic granule cells that are born following pilocarpine-induced seizures. Neuroscience Lett. 422:136-140.
  16. Scharfman HE, Hintz TM, Gomez J, Stormes KA, Barouk S, Malthankar-Phatak GH, McCloskey DP, Luine VN, and MacLusky NJ (2007) Changes in hippocampal function in ovariectomized rats after sequential low doses of estradiol to simulate the preovulatory estrogen surge. Eur. J. Neurosci. 26:2595-612.
  17. Walling SG, Rigoulot MA and Scharfman HE (2007) Acute and chronic changes in glycogen phosphorylase in hippocampus and entorhinal cortex after status epilepticus in the adult male rat. Eur. J. Neurosci. 26:178-189.
  18. Winawer MR, Makarenko N, McCloskey DP, Hintz TM, Nair N, Palmer AA and Scharfman HE (2007) Acute and chronic responses to the convulsant pilocarpine in DBA and A/J mice. Neuroscience. 149:465-475.
  19. MacBeth AH, Scharfman HE, MacLusky NJ and Luine VN (2008) Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF). Horm Beh., 76:36-44.
  20. Nicoletti JN, Shah SK, McCloskey DP, Goodman JH, Elkady A, Atassi H, Hylton D, Rudge JS, Scharfman HE and Croll SD (2008) Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus. Neuroscience, 151:232-241.
  21. McCloskey DP, Hintz TM and Scharfman HE (2008) Modulation of vascular endothelial growth factor (VEGF) expression in motor neurons and its electrophysiological effects. Brain Res. Bull. 76:36-44.
  22. Scharfman HE, Hintz TM, Kim M and MacLusky NJ (2009) Seizures and reproductive function: insights from an animal model of epilepsy. Ann Neurol. 54:687-697.
  23. Myers CE and Scharfman HE (2009) The role of hilar neurons in pattern separation: a computational approach. Hippocampus. 19:321-337.
  24. Kimura A, Hsu M, Seldin M, Scharfman HE and Binder DK (2010) Protective role of aquaporin-4 water channels following contusion spinal cord injury. Ann. Neurol. 67:794-801.
  25. Pierce JP, McCloskey DP and Scharfman HE (2011) Morphometry of hilar ectopic granule cells in the rat. J Comp Neurol. 519(6):1196-218. doi: 10.1002/cne.22568. PMID: 21344409
  26. Barouk S, Hintz T, Li P, Duffy AM, MacLusky NJ and Scharfman HE (2011) 17β-estradiol increases astrocytic vascular endothelial growth factor (VEGF) in adult female rat hippocampus.

Endocrinology. 152(5):1745-51. doi: 10.1210/en.2010-1290. PMID: 21343256

  1. Myers CE and Scharfman HE (2011) Pattern separation in the dentate gyrus: a role for the CA3 backprojection. Hippocampus. 21(11):1190-215. doi: 10.1002/hipo.20828. PMID: 20683841
  2. 73. Kimura A, Hsu M, Seldin M, Verkman AS, Scharfman HE and Binder DK (2010) Protective role of aquaporin-4 water channels after contusion spinal cord injury. Ann Neurol. 67(6):794-801. doi: 10.1002/ana.22023. PMID: 20517941
  3. Scharfman HE, Kramár EA, Luine V and Srivastava DP (2013) Introduction to steroid hormone actions in the CNS: the role of brain-derived neurotrophic factor (BDNF). Neuroscience. 239:1-2. doi: 10.1016/j.neuroscience.2012.10.022. PMID: 23164677
  4. Scharfman HE (2012) Untangling Alzheimer's disease and epilepsy. Epilepsy Curr. 12(5):178-83. doi: 10.5698/1535-7511-12.5.178. PMID: 23118602
  5. Lee H, Dvorak D, Kao HY, Duffy ÁM, Scharfman HE and Fenton AA (2012) Early cognitive experience prevents adult deficits in a neurodevelopmental schizophrenia model. Neuron. 75(4):714-24. doi: 10.1016/j.neuron.2012.06.016. PMID: 22920261
  6. Scharfman HE (2012) Alzheimer's disease and epilepsy: insight from animal models.

Future Neurol. 7(2):177-192. doi: 10.2217/fnl.12.8. PMID: 22723738

  1. Scharfman HE and Pierce JP (2012) New insights into the role of hilar ectopic granule cells in the dentate gyrus based on quantitative anatomic analysis and three-dimensional reconstruction. Epilepsia. 53 Suppl 1(0 1):109-15. doi: 10.1111/j.1528 1167.2012.03480.x. PMID: 22612815
  2. Chakraborty G, Magagna-Poveda A, Parratt C, Umans JG, MacLusky NJ and Scharfman HE (2012) Reduced hippocampal brain-derived neurotrophic factor (BDNF) in neonatal rats after prenatal exposure to propylthiouracil (PTU). Endocrinology. 153(3):1311-6. doi: 10.1210/en.2011-1437. PMID: 22253429
  3. McCloskey DP and Scharfman HE (2011) Progressive, potassium-sensitive epileptiform activity in hippocampal area CA3 of pilocarpine-treated rats with recurrent seizures.

Epilepsy Res. 97(1-2):92-102. doi: 10.1016/j.eplepsyres.2011.07.008. PMID: 21880468

  1. Skucas VA, Mathews IB, Yang J, Cheng Q, Treister A, Duffy AM, Verkman AS, Hempstead BL, Wood MA, Binder DK and Scharfman HE (2011) Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4.
  2. Neurosci. 31(17):6392-7. doi: 10.1523/JNEUROSCI.6249-10.2011. PMID: 21525279
  3. Duffy AM, Schaner MJ, Wu SH, Staniszewski A, Kumar A, Arévalo JC, Arancio O, Chao MV and Scharfman HE (2011) A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons. Exp Neurol. 229(2):409-20. doi: 10.1016/j.expneurol.2011.03.008. PMID: 21419124
  1. Skucas VA, Duffy AM, Harte-Hargrove LC, Magagna-Poveda A, Radman T, Chakraborty G, Schroeder CE, MacLusky NJ and Scharfman HE (2013) Testosterone depletion in adult male rats increases mossy fiber transmission, LTP, and sprouting in area CA3 of hippocampus. J. Neurosci. 33(6):2338-55. doi: 10.1523/JNEUROSCI.3857-12.2013. PMID: 23392664
  2. Yang J, Harte-Hargrove LC, Siao CJ, Marinic T, Clarke R, Ma Q, Jing D, LaFrancois JJ, Bath KG, Mark W, Ballon D, Lee FS, Scharfman HE and Hempstead BL (2014) proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus. Cell Rep. 7(3):796-806. doi: 10.1016/j.celrep.2014.03.040. PMID: 24746813
  3. Pearce PS, Friedman D, LaFrancois JJ, Iyengar SS, Fenton AA, Maclusky NJ and Scharfman HE (2014) Spike-wave discharges in adult Sprague-Dawley rats and their implications for animal models of temporal lobe epilepsy. Epilepsy Behav. 32:121-31. doi: 10.1016/j.yebeh.2014.01.004. PMID: 24534480
  4. 86. VonDran MW, LaFrancois JJ, Padow VA, Friedman WJ, Scharfman HE, Milner TA and Hempstead BL (2014) p75NTR, but not proNGF, is upregulated following status epilepticus in mice. ASN Neuro. 6(5):1759091414552185. doi: 10.1177/1759091414552185. PMID: 25290065
  5. Cho KO, Lybrand ZR, Ito N, Brulet R, Tafacory F, Zhang L, Good L, Ure K, Kernie SG, Birnbaum SG, Scharfman HE, Eisch AJ and Hsieh J (2015) Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline. Nat Commun. 6:6606. doi: 10.1038/ncomms7606. PMID: 25808087
  6. Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R and Scharfman HE (2015) Suppression of adult neurogenesis increases the acute effects of kainic acid. Exp Neurol. 264:135-49. doi:10.1016/j.expneurol.2014. 11.009. Epub 2014 Dec 2. PMID: 25476494
  7. Blackstad JS, Osen KK, Scharfman HE, Storm-Mathisen J, Blackstad TW and Leergaard TB (2016) Observations on hippocampal mossy cells in mink (Neovison vison) with special reference to dendrites ascending to the granular and molecular layers. Hippocampus. ;26(2):229-45. doi: 10.1002/hipo.22518. PMID: 26286893
  8. Harte-Hargrove LC, Varga-Wesson A, Duffy AM, Milner TA and Scharfman HE (2015) Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat. J. Neurosci. 35(4):1723-38. doi: 10.1523/JNEUROSCI. 0820-14.2015. PMID: 25632146
  9. 91. Duffy AM, Morales-Corraliza J, Bermudez-Hernandez KM, Schaner MJ, Magagna-Poveda A, Mathews PM and Scharfman HE (2015) Entorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age. Neurobiol Aging. 2015 Jan;36(1):134-48. doi: 10.1016/j. neurobiolaging.2014.07.001. Epub 2014 Jul 11. PMID: 25109765
  10. D'Amour J, Magagna-Poveda A, Moretto J, Friedman D, LaFrancois JJ, Pearce P, Fenton AA, MacLusky NJ and Scharfman HE (2015) Interictal spike frequency varies with ovarian cycle stage in a rat model of epilepsy. Exp Neurol. 269:102-19. doi:10.1016/j.expneurol. 2015.04.003. PMID: 25864929
  11. Kam K, Duffy ÁM, Moretto J, LaFrancois JJ and Scharfman HE (2016) Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology.

Sci Rep. 6:20119. doi: 10.1038/srep20119. PMID: 26818394

  1. Drew LJ, Kheirbek MA, Luna VM, Denny CA, Cloidt MA, Wu MV, Jain S, Scharfman HE and Hen R (2016) Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons. Hippocampus. 26(6):763-78. doi: 10.1002/hipo.22557. PMID: 26662922
  2. Scharfman HE and Myers CE (2016) Corruption of the dentate gyrus by "dominant" granule cells: Implications for dentate gyrus function in health and disease. Neurobiol Learn Mem. 129:69-82. doi: 10.1016/j.nlm.2015.09.005. PMID: 26391451
  3. Mendell AL, Atwi S, Bailey CD, McCloskey D, Scharfman HE and MacLusky NJ (2017) Expansion of mossy fibers and CA3 apical dendritic length accompanies the fall in dendritic spine density after gonadectomy in male, but not female, rats. Brain Struct Funct. 222(1):587-601. doi: 10.1007/s00429-016-1237-6. Epub 2016 Jun 9. PMID: 27283589
  1. Greenwood SG, Montroull L, Volosin M, Scharfman HE, Teng KK, Light M, Torkin R, Maxfield F, Hempstead BL, Friedman WJ (2017) A novel neuroprotective mechanism for lithium that prevents association of the p75NTR-sortilin receptor complex and attenuates proNGF-induced neuronal death in vitro and in vivo. eNeuro. 5(1): ENEURO.0257-17.2017. doi: 10.1523/ENEURO.0257-17.2017. PMID: 29349290
  2. You JC, Muralidharan K, Park JW, Petrof I, Pyfer MS, Corbett BF, LaFrancois JJ, Zheng Y, Zhang X, Mohila CA, Yoshor D, Rissman RA, Nestler EJ, Scharfman HE and Chin J (2017) Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. Nat Med. 23(11):1377-1383. doi: 10.1038/nm.4413. PMID: 29035369
  3. Magagna-Poveda A, Moretto JN and Scharfman HE (2017) Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats. Brain Struct Funct. 222(9):4219-4237. doi: 10.1007/s00429-017-1457-4. PMID: 28656372
  4. Bermudez-Hernandez K, Lu YL, Moretto J, Jain S, LaFrancois JJ, Duffy AM and Scharfman HE (2017) Hilar granule cells of the mouse dentate gyrus: effects of age, septotemporal location, strain, and selective deletion of the proapoptotic gene BAX. Brain Struct Funct. 222(7):3147-3161. doi: 10.1007/s00429-017-1391-5. PMID: 28314928
  5. Moretto JN, Duffy ÁM and Scharfman HE (2017) Acute restraint stress decreases c-fos immunoreactivity in hilar mossy cells of the adult dentate gyrus. Brain Struct Funct. 22(5): 2405-2419. doi: 10.1007/s00429-016-1349-z. PMID: 28190104
  6. Botterill JJ, Lu YL, LaFrancois JJ, Bernstein HL, Alcantara-Gonzalez D, Jain S, Leary P and Scharfman HE (2019) An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy. Cell Rep. 29(9):2875-2889.e6. doi:10.1016/j.celrep. 2019. 10. 100. PMID: 31775052
  7. Bernstein HL, Lu YL, Botterill JJ and Scharfman HE (2019) Novelty and novel objects increase c-Fos immunoreactivity in mossy cells in the mouse dentate gyrus. Neural Plast. 2019:1815371. doi: 10.1155/2019/1815371. PMID: 31534449
  1. Saadipour K, Tiberi A, Lombardo S, Grajales E, Montroull L, Mañucat-Tan NB, LaFrancois JJ, Cammer M, Mathews PM, Scharfman HE, Liao FF, Friedman WJ, Zhou XF, Tesco G and Chao MV (2019) Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor. Mol Cell Neurosci. 99:103395. doi: 10.1016/j.mcn.2019.103395. PMID: 31422108
  2. Fu CH, Iascone DM, Petrof I, Hazra A, Zhang X, Pyfer MS, Tosi U, Corbett BF, Cai J, Lee J, Park J, Iacovitti L, Scharfman HE, Enikolopov G and Chin J (2019) Early seizure activity accelerates depletion of hippocampal neural stem cells and impairs spatial discrimination in an Alzheimer's disease model. Cell Rep. 27(13):3741-3751.e4. doi: 10.1016/j.celrep. 2019.05.101. PMID: 31242408
  3. Luna VM, Anacker C, Burghardt NS, Khandaker H, Andreu V, Millette A, Leary P, Ravenelle R, Jimenez JC, Mastrodonato A, Denny CA, Fenton AA, Scharfman HE and Hen R (2019) Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus. Science. 364(6440):578-583. doi: 10.1126/science.aat8789. PMID: 31073064
  4. Jain S, LaFrancois JJ, Botterill JJ, Alcantara-Gonzalez D and Scharfman HE (2019) Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures. Hippocampus. 29(8):683-709. doi: 10.1002/hipo.23062. PMID: 30672046
  5. Stephens GS, Fu CH, St Romain CP, Zheng Y, Botterill JJ, Scharfman HE, Liu Y and Chin J (2020) Genes bound by ΔFosB in different conditions with recurrent seizures regulate similar neuronal functions. Front Neurosci. 14:472. doi: 10.3389/fnins.2020.00472. PMID: 32536852
  6. Ma Y, Bayguinov PO, McMahon SM, Scharfman HE, Jackson MB (2021)
    Direct synaptic excitation between hilar mossy cells revealed with a targeted voltage sensor.     Hippocampus. 31(11):1215-1232. doi: 10.1002/hipo.23386. PMID: 34478219
  7. Botterill JJ, Gerencer KJ, Vinod KY, Alcantara-Gonzalez D and Scharfman HE (2021) Dorsal and ventral mossy cells differ in their axonal projections throughout the dentate gyrus of the mouse hippocampus. Hippocampus. 31(5):522-539. doi: 10.1002/hipo.23314. PMID: 33600026
  8. Alcantara-Gonzalez D, Chartampila E, Criscuolo C and Scharfman HE (2021) Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine. Neurobiol Dis. 152:105274. doi: 10.1016/j.nbd.2021.105274. PMID: 33484828
  9. Botterill JJ, Vinod KY, Gerencer KJ, Teixeira CM, LaFrancois JJ and Scharfman HE J (2021) Bidirectional regulation of cognitive and anxiety-like behaviors by dentate gyrus mossy cells in male and female mice. J. Neurosci. 41(11):2475-2495. doi: 10.1523/JNEUROSCI.1724-20.2021. PMID: 33472828
  10. Cruz E, Descalzi G, Steinmetz A, Scharfman HE, Katzman A and Alberini CM (2021) CIM6P/IGF-2 receptor ligands reverse deficits in Angelman syndrome model mice. Autism Res. 14(1):29-45. doi: 10.1002/aur.2418. PMID: 33108069
  11. Lisgaras CP and Scharfman HE (2022) High-frequency oscillations (250-500 Hz) in animal models of Alzheimer's disease and two animal models of epilepsy. Epilepsia. doi: 10.1111/epi.17462. PMID: 36346209
  12. Whitebirch AC, LaFrancois JJ, Jain S, Leary P, Santoro B, Siegelbaum SA and Scharfman HE (2022) Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron. 110(19):3121-3138.e8. doi: 10.1016/j.neuron.2022.07.020. PMID: 35987207
  13. Lisgaras CP and Scharfman HE (2022) Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice. Neurobiol Dis. 166:105637. doi: 10.1016/j.nbd.2022.105637. PMID: 35091040
  14. Criscuolo C, Chartampila E, Ginsberg SD, Scharfman HE (2023) Dentate gyrus granule cells show stability of BDNF protein expression in mossy fiber axons with age and resistance to Alzheimer's disease neuropathology in a mouse model. eNeuro. ENEURO.0192-23.2023. doi: 10.1523/ENEURO.0192-23.2023. PMID: 38164567
  15. 118. Lisgaras CP, Scharfman HE (2023) Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum. Neurobiol Dis. 187:106294. doi: 10.1016/j.nbd.2023.106294. PMID: 37714307
  16. Whitebirch AC, Santoro B, Barnett A, Lisgaras CP, Scharfman HE, Siegelbaum SA. (2023) Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy. J. Neurosci. 43(41):6930-6949. doi: 10.1523/JNEUROSCI.2091-22.2023. PMID: 37643861
  17. Jain S, LaFrancois JJ, Gerencer K, Botterill JJ, Kennedy M, Criscuolo C, Scharfman HE. (2024) Increasing adult neurogenesis protects mice from epilepsy. Elife. 12:RP90893. doi: 10.7554/eLife.90893. PMID: 39446467
  18. 121. Chartampila E, Elayouby KS, Leary P, LaFrancois JJ, Alcantara-Gonzalez D, Jain S, Gerencer K, Botterill JJ, Ginsberg SD,Scharfman HE. (2024) Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease. 12:RP89889. doi: 10.7554/eLife.89889. PMID: 38904658
  19. Rosenberg EC, Chamberland S, Bazelot M, Nebet ER, Wang X, McKenzie S, Jain S, Greenhill S, Wilson M, Marley N, Salah A, Bailey S, Patra PH, Rose R, Chenouard N, Sun SED, Jones D, Buzsáki G, Devinsky O, Woodhall G, Scharfman HE, Whalley BJ, Tsien RW. (2023) Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity. Neuron. 111(8):1282-1300.e8. doi: 10.1016/j.neuron.2023.01.018. PMID: 36787750
  20. Bernstein HL, Lu YL, Botterill JJ, Duffy ÁM, LaFrancois JJ, Scharfman HE (2025)
    Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices. Hippocampus. 35(1):e23652. doi: 10.1002/hipo.23652. PMID: 39665517
  21. Alcantara-Gonzalez D, Kennedy M, Criscuolo C, Botterill J, Scharfman HE (2025) Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease Alzheimers Research & Therapy. 17(1):105. doi: 10.1186/s13195-025-01747-1. PMID: 40375112
  22. Lisgaras CP, Scharfman HE High frequency oscillations (>250Hz) outnumber interictal spikes in preclinical studies of Alzheimer's disease. bioRxiv [Preprint]. 2:2023.10.30.564797. doi: 10.1101/2023.10.30.564797. PMID: 37961135

REVIEWS AND BOOK CHAPTERS

  1. Schwartzkroin PA, Scharfman HE and Sloviter RS (1990) Similarities in circuitry between Ammon's horn and dentate gyrus: local interactions and parallel processing. Prog. Brain Res. 83:269-287.
  2. Scharfman HE (1992) Differentiation of rat dentate neurons by morphology and electrophysiology in hippocampal slices: granule cells, spiny hilar cells and aspiny, "fast-spiking" cells. In: The Dentate Gyrus and Its Role in Seizures. Eds: Ribak CE, Gall C and Mody I. New York, Elsevier, pp. 93-109.
  3. Scharfman HE (1993) Pre- and postsynaptic actions of somatostatin in rat and rabbit hippocampal slices. In: Presynaptic Receptors in the CNS: Physiology and Pharmacology. Eds: Dunwiddie T and Lovinger D. Boston, Birkäuser, pp. 42-70.
  4. Scharfman HE (1999) The role of nonprincipal cells in dentate gyrus excitability and its relevance to animal models of epilepsy and temporal lobe epilepsy. In: Basic Mechanisms of the Epilepsies: Molecular and Cellular Approaches, Third edition. Eds: Delgado-Esqueta AV, Wilson W, Olsen RW and Porter RJ. New York, Lippincott-Raven, pp. 805-820.
  5. Scharfman HE, Goodman JH and Schwarcz R (2000) Electrophysiological effects of exogenous and endogenous kynurenic acid in the rat brain: studies in vivo and in vitro. Amino Acids 19:283-297.
  6. Binder DK, Croll SD, Gall CM and Scharfman HE (2001) BDNF and epilepsy: too much of a good thing? Trends Neurosci. 24:47-53.
  7. Schwarcz R, Scharfman HE and Bertram EH (2001) Temporal lobe epilepsy: renewed emphasis on extrahippocampal areas. In: ACNP 5th Generation of Progress. Eds: Davis KL, Charney D, Coyle JT and Nemeroff C Lippincott Williams and Wilkins. pp. 1843-1855.
  8. Scharfman HE (2002) The parahippocampal region in temporal lobe epilepsy. In: The Parahippocampal Region: Organization and Role in Cognitive Functions. Eds. Witter MP and Wouterlood FG. Oxford University Press, pp. 319-338.
  9. Scharfman HE (2002) Epilepsy as an example of neural plasticity. The Neuroscientist 8:155-174.
  10. Scharfman HE (2002) Does the development of a GABAergic phenotype by hippocampal dentate gyrus granule cells contribute to epileptogenesis? Epilepsy Currents 2:63-65.
  11. Scharfman HE (2002) Brain-derived neurotrophic factor enhances fast excitatory synaptic transmission in human epileptic dentate gyrus. Epilepsy Currents 2:93-94.
  12. Scharfman HE (2002) Grafts of encapsulated fibroblasts engineered to release an anticonvulsant substrate. Epilepsy Currents 2:125-126.
  13. Scharfman HE (2002) A novel animal model of epilepsy caused by inhibiting neuronal activity during development. Epilepsy Currents 2:127-128.
  14. Scharfman HE (2004) Functional implications of seizure-induced neurogenesis. In: Recent Advances in Epilepsy Research. Eds. Binder DK and Scharfman HE. New York, Landes/Kluwer Press.
  15. Croll SD, Goodman JH and Scharfman HE (2004) VEGF and seizures: a double-edged Sword? In: Recent Advances in Epilepsy Research. Eds. Binder DK and Scharfman HE. New York, Landes/Kluwer Press.
  16. Binder DK and Scharfman HE (2004) Brain-derived neurotrophic factor. Growth Factors 22:123-131.
  17. Scharfman HE (2005) BDNF and the mossy fibers: implications for epilepsy. In: Synaptic plasticity and transynaptic signaling. Eds. Stanton PK, Bramham C and Scharfman HE, New York, Springer Science and Business Media.
  18. Scharfman HE and Gray WP (2005) NPY and plasticity in the dentate gyrus after seizures. In: NPY Family of Peptides in Inflammation, Immune Disorders, Angiogenesis, and Cancer. Eds: Zukowska Z and Feuerstein G, Switzerland, Birkhauser Verlag.
  19. Gray WP and Scharfman HE (2005) NPY and neurogenesis. In: NPY Family of Peptides in Inflammation, Immune Disorders, Angiogenesis, and Cancer. Eds: Zukowska Z and Feuerstein G Switzerland, Birkhauser Verlag.
  20. Scharfman HE and MacLusky NM (2005) Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends Neurosci. 28:79-85.
  21. Croll SD, McCloskey DP, Nicoletti JN and Scharfman HE (2005) VEGF as a novel seizure therapeutic: killing two birds with one stone. In: Growth Factors and Epilepsy. Eds. Binder DK and Scharfman HE. New York, Nova Sciences.
  22. Scharfman HE (2005) Seizure-induced neurogenesis and its dependence on growth factors and cytokines. In: Growth Factors and Epilepsy. Eds. Binder DK and Scharfman HE. New York, Nova Sciences.
  23. Scharfman HE (2005) The absence of information about hormones and absence. Epilepsy Currents 5:101-103.
  24. Scharfman HE (2005) BDNF and epilepsy: a missing link? Epilepsy Currents 5:83-88.

Scharfman HE and MacLusky NJ (2005) Similarities between BDNF and estrogen in hippocampus: coincidence or clue? Trends Neurosci. 28:79-85.

  1. Scharfman HE and MacLusky NJ (2006) Estrogen and BDNF: complexity of steroid hormone-growth factor interactions. Frontiers Neuroendocrinol. 27:415-435.
  2. Scharfman HE and MacLusky NJ (2006) The influence of gonadal hormones on excitability, seizures and epilepsy in the female. Epilepsia 47:1423-1440.
  3. Scharfman HE and Pedley TA (2006) Temporal lobe epilepsy. In: The Neurobiology of Disease. Ed: Gilman, S. New York, Academic Press, pp. 349-370.
  4. Scharfman HE and Hen R (2007) Is more neurogenesis better? Science. 315:316-318.
  5. Scharfman HE and Gray WP (2007) Relevance of seizure-induced neurogenesis to the etiology of temporal lobe epilepsy. Epilepsia. 48 (Suppl 2):33-41.
  6. Scharfman HE and Schwarcz R (2007) Neuromodulators in seizures, epileptogenesis, and epilepsy. In: Epilepsy: A Comprehensive Guide. Eds: Engel J, Pedley TA. New York, Lippincott-Raven, pp. 289-306.
  7. Scharfman HE (2007) The neurobiology of epilepsy. Curr Neurosci Res Rep. 7:348-354.
  8. Scharfman HE (2007) The CA3 “back” projection to the dentate gyrus. Prog Brain Res. 163:627-637.
  9. Amaral DG, Scharfman HE and Levanex P (2007) The dentate gyrus: fundamental neuroanatomical organization (the dentate gyrus for “dummies”). Prog Brain Res. 163:3-22.
  10. Scharfman HE and MacLusky NJ (2008) Estrogen actions in the brain: relevance to neurological disorders. Headache 48 (S2):77-89.
  11. Scharfman HE (2009) The role of neurotrophins in excitability in hippocampus and its potential relevance to epilepsy. In: The Encyclopedia of Basic Epilepsy Res. Ed: Schwartzkroin PA. New York: Elsevier.
  12. Scharfman HE (2009) Neurogenesis in the dentate gyrus and its potential role in epileptogenesis. In: The Encyclopedia of Basic Epilepsy Res. Ed: Schwartzkroin PA. New York: Elsevier.
  13. Scharfman HE and McCloskey DP (2009) Postnatal neurogenesis as a potential therapeutic target in epilepsy. Epilepsy Res. 85:150-161.
  14. McNamara JO and Scharfman HE (2010) Temporal lobe epilepsy and the BDNF receptor, TrkB. In: Jasper’s Basic Mechanisms of the Epilepsies. Eds: Noebels J, Rogawski M, Avoli M, Olsen R, Delgado-Escueta A. New York: Oxford University Press.
  15. Schroeder CE, Wilson DA, Radman T, Scharfman HE and Lakatos P (2010) Dynamics of active sensing and perceptual selection. Curr Opin. Neurol. 20:172-176.
  16. Scharfman HE (2010) Seizing an opportunity: a broader definition of epilepsy will lead to better treatment. Cerebrum, http://www.dana.org/news/cerebrum/detail.aspx?id=29090
  17. Scharfman HE and Myers CE (2013) Hilar mossy cells of the dentate gyrus: a historical perspective. Front Neural Circuits. 6:106. doi: 10.3389/fncir.2012.00106. PMID: 23420672
  18. Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M and Scharfman HE (2013) Authors' response to letter by A. Mazarati. Epilepsia. 54(12):2229-30. doi: 10.1111/epi.12414. PMID: 24304440
  19. Scharfman HE (2013) Cutting through the complexity: the role of brain-derived neurotrophic factor in post-traumatic epilepsy (Commentary on Gill et al.). Eur J. Neurosci. 38(11):3552-3. doi: 10.1111/ejn.12419. PMID: 24289826
  20. Scharfman HE and Chao MV (2013) The entorhinal cortex and neurotrophin signaling in Alzheimer's disease and other disorders. Cogn Neurosci. 4(3-4):123-35. doi: 10.1080/17588928.2013.826184. PMID: 24168199
  21. Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M and Scharfman HE (2013) Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. Epilepsia. 54 Suppl 4(0 4):44-60. doi: 10.1111/epi.12298. PMID: 23909853
  22. Scharfman HE (2013) Preface to the special issue: The future of translational epilepsy research. Epilepsy Behav. 26(3):209. doi: 10.1016/j.yebeh.2012.12.016. PMID: 23352321
  23. Chin J and Scharfman HE (2013) Shared cognitive and behavioral impairments in epilepsy and Alzheimer's disease and potential underlying mechanisms. Epilepsy Behav. 26(3):343-51. doi: 10.1016/j.yebeh.2012.11.040. PMID: 23321057
  24. Bath KG and Scharfman HE (2013) Impact of early life exposure to antiepileptic drugs on neurobehavioral outcomes based on laboratory animal and clinical research. Epilepsy Behav. 26(3):427-39. doi: 10.1016/j.yebeh.2012.10.031. PMID: 23305780
  25. Harte-Hargrove LC, Maclusky NJ and Scharfman HE (2013) Brain-derived neurotrophic factor-estrogen interactions in the hippocampal mossy fiber pathway: implications for normal brain function and disease. Neuroscience. 239:46-66. doi: 10.1016/j.neuroscience. 2012.12.029. PMID: 23276673
  26. Scharfman HE and MacLusky NJ (2014) Sex differences in the neurobiology of epilepsy: a preclinical perspective. Neurobiol Dis. 72 Pt B:180-92. doi: 10.1016/j.nbd. 2014.07.004. PMID: 25058745
  27. Scharfman HE and Brooks-Kayal AR (2014) Is plasticity of GABAergic mechanisms relevant to epileptogenesis? Adv Exp Med Biol. 813:133-50. doi: 10.1007/978-94-017-8914-1_11. PMID: 25012373
  28. Fisher RS, Scharfman HE and deCurtis M (2014) How can we identify ictal and interictal abnormal activity? Adv Exp Med Biol. 813:3-23. doi: 10.1007/978-94-017-8914-1_1. PMID: 25012363
  29. Scharfman HE and Buckmaster PS (2014) Preface. Adv Exp Med Biol. 2014;813:xv-xviii. PMID: 25371938
  30. Scharfman HE and MacLusky NJ (2014) Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. Neuropharmacology. 76 Pt C(0 0):696-708. doi: 10.1016/j.neuropharm.2013.04.029. PMID: 23660230
  31. Scharfman HE, MacLusky NJ (2014) Sex differences in the neurobiology of epilepsy: a preclinical perspective. Neurobiol Dis. 72 Pt B:180-92. doi:10.1016/j.nbd.2014.07. 004. PMID: 25058745
  1. Scharfman HE (2015) Neuroscience. Metabolic control of epilepsy. Science. 347(6228):1312-3. doi: 10.1126/science.aaa9607. PMID: 25792315
  2. Scharfman HE and Bernstein HL (2015) Potential implications of a monosynaptic pathway from mossy cells to adult-born granule cells of the dentate gyrus. Front Syst Neurosci. 9:112. doi: 10.3389/fnsys.2015.00112. PMID: 26347618
  3. Scharfman HE (2016) The enigmatic mossy cell of the dentate gyrus. Nat Rev Neurosci. 2016 Sep;17(9):562-75. doi: 10.1038/nrn.2016.87. Epub 2016 Jul 28. PMID: 27466143
  4. Scharfman HE (2018) Controlling learning and epilepsy together. Science. 359(6377):740-741. doi: 10.1126/science.aas8993. PMID: 29449476
  5. Scharfman HE (2018) Advances in understanding hilar mossy cells of the dentate gyrus. Cell Tissue Res. 373(3):643-652. doi: 10.1007/s00441-017-2750-5. PMID: 29222692
  6. Scharfman HE and MacLusky NJ (2017) Sex differences in hippocampal area CA3 pyramidal cells. J. Neurosci Res. 95(1-2):563-575. doi:10.1002/jnr.23927. PMID: 27870399
  7. Scharfman HE (2019) The dentate gyrus and temporal lobe epilepsy: an "exciting" era. Epilepsy Curr. 19(4):249-255. doi: 10.1177/1535759719855952. PMID: 31232111
  8. Scharfman HE (2024) The diverse roles of mossy cells in the normal brain, epileptogenesis, and chronic epilepsy.In: Jasper’s Basic Mechanisms of the Epilepsies. Eds: Noebels JL, Avoli M, Rogawski MR, Vezzani A, Delgado-Escueta AV.
  9. Scharfman HE (2025) Towards an understanding of the dentate gyrus hilus. Hippocampus. 35(1):e23677. doi: 10.1002/hipo.23677.PMID: 39721944

 PROCEEDINGS

  1. Scharfman HE (2000) Epileptogenesis in the parahippocampal region: parallels with the dentate gyrus. In: The Parahippocampal Region: Basic Science and Clinical Implications. Eds: Scharfman HE, Witte MP and Schwarcz R New York, New York Academy of Sciences, pp. 305-327.
  2. Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J, Morrison J, Nehlig A, Prasad A, Wilcox KS, Jette N and Pohlmann-Eden B (2018) Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research? Epilepsy Behav. 78:302-312. doi: 10.1016/j.yebeh.2017.09.016. PMID: 29097123
  3. Harte-Hargrove LC, French JA, Pitkänen A, Galanopoulou AS, Whittemore V and Scharfman HE (2017) Common data elements for preclinical epilepsy research: Standards for data collection and reporting. A TASK3 report of the AES/ILAE Translational Task Force of the ILAE. Epilepsia. 58 Suppl 4(Suppl 4):78-86. doi: 10.1111/epi.13906. PMID: 29105074
  4. Harte-Hargrove LC, Galanopoulou AS, French JA, Pitkänen A, Whittemore V, Scharfman HE (2018) Common data elements (CDEs) for preclinical epilepsy research: Introduction to CDEs and description of core CDEs. A TASK3 report of the ILAE/AES joint translational task force. Epilepsia Open. 3(Suppl Suppl 1):13-23. doi: 10.1002/epi4.12234. PMID: 30450483
  5. Scharfman HE, Galanopoulou AS, French JA, Pitkänen A, Whittemore V and Harte-Hargrove LC (2018) Preclinical common data elements (CDEs) for epilepsy: A joint ILAE/AES and NINDS translational initiative. Epilepsia Open. 3(Suppl Suppl 1):9-12. doi: 10.1002/ epi4. 12235. PMID: 30450482
  6. Gorter JA, van Vliet EA, Dedeurwaerdere S, Buchanan GF, Friedman D, Borges K, Grabenstatter H, Lukasiuk K, Scharfman HE and Nehlig A (2018) A companion to the preclinical common data elements for physiologic data in rodent epilepsy models. A report of the TASK3 Physiology Working Group of the ILAE/AES Joint Translational Task Force. Epilepsia Open. 3(Suppl Suppl 1):69-89. doi: 10.1002/epi4.12261. PMID: 30411072

BOOKS EDITED

  1. Scharfman HE, Witter MP and Schwarcz R, Eds. (2000) The Parahippocampal Region: Basic Science and Clinical Implications. New York, New York Academy of Sciences.
  2. Binder DK and Scharfman HE, Eds. (2004) Recent Advances in Epilepsy Research. New York, Kluwer Press.
  3. Binder DK and Scharfman HE, Eds. (2005) Growth Factors and Epilepsy. New York, Nova Sciences.
  4. Stanton PK, Bramham CV and Scharfman HE, Eds. (2005) Synaptic plasticity and transsynaptic signaling. New York, Springer Science & Business Media.
  5. Scharfman HE, Ed. (2007) The Dentate Gyrus: A Comprehensive Guide to Structure, Function, and Clinical Implications. New York, Elsevier.